This review, which focuses on ePrescribing in primary care, revises the International Review of ePrescribing and Electronic Transfer of Prescriptions published in 2012. It is based on documentation that was available on national ePrescribing programmes and on interviews with four European programme leads. The review defines ePrescribing as the generation of prescription information, the transfer of prescription information and the dispensing of the prescription electronically using a dedicated system. Itoutlines key areas of national ePrescribing programmes, including the strategy, governance and possible implementation models. Furthermore, it summarizes progress since 2012 on the Irish ePrescribing program.